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10.1523/JNEUROSCI.18-23-09620.1998 112 LewerenzJ.MaherP.MethnerA

In challenge infections using WT UTI89 and UTI89 hlyA strains in nave, resolved and sensitized mice, we observed that hlyA infection, which does not activate caspase-1-mediated pyroptotic cell death, showed significantly increased bacterial burdens in sensitized mice compared with WT mice, whereas no differences were observed in nave and resolved mice (Fig