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However, increasing oral supplement doses (within safe limits) while awaiting medical review is generally considered safe, as B12 has very low toxicity and excess is excreted through the kidneys

A recent meta-analysis showed that long-term use of low-dose (2,000 mg/day) L-carnitine could reduce TC and TG in overweight patients with liver disease, especially those with chronic hepatitis C (82)

Several studies in patients with psoriasis and psoriatic arthritis have observed an increased abundance of Firmicutes in the gut microbiota (162)

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