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Cancer cells have also been found to release a type of metabolites in a specific genetic context termed oncometabolite, which indirectly facilitates tumorigenesis through immunomodulation (142)

The mitochondrial pathway is well-known for its involvement in GM-induced apoptosis, with ROS proposed as the key mediators of this mechanism ( BV has been demonstrated to exhibit different biological activities, such as anti-inflammatory and antioxidant properties

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Chronic ethanol consumption also affects norepinephrine and dopamine systems, leading to disruptions in the remodeling of neurotransmitter receptors