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Hagerman et al., 2014)

Driessens, M

WangYSunXMaRZhangXJiSLiuZet al

If acetylcysteine therapy is discontinued upon a toxicologists advice and liver function tests show improvement but have not yet returned to baseline or normal values, it is expected that liver function will normalize within two weeks

instead, all attempts yielded clones that had reverted to the parental wildtype strain, a result we obtained across multiple attempts in different genetic backgrounds, screening more than 3 dozen clones