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peripheral vascular thrombosis Hematological: Polycythemia vera (a rare type of blood cancer) Gastrointestinal: Mild, transient diarrhea Dermatological: Itching

A complete blood count and differential, liver function tests, and renal function with estimated glomerular filtration rate point toward the hepatic, renal, and hematologic causes that account for most disease-associated elevation

What happens with extended use over months or years is unknown territory

On top of that, it's important to know that the majority of water-soluble nutrients cannot be stored by our body for later use, meaning that our system will only be able to absorb so much in a given period