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Relative mRNA expression of Gclm (p = 0.0026), Hmox1 , Nqo1 , and Slc7a11 (d) and representative immunohistochemistry of indicated proteins (e) in Gclc WT and Gclc KO tumors (n = 6 representative from 3 independent experiments)

Dysregulated gut homeostasis observed prior to the accumulation of the brain amyloid- in Tg2576 mice

Acetylation absence in the mouse p53 K98 site and on other positions in the DNA-binding domain can result in the loss of tumor suppression functions in xenografts and ferroptosis (Wang et al., 2016)

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16TH Annual Behavior, Biology, and Chemistry: Translational Research in Substance Use Disorders, San Antonio, Texas | Embassy Landmark | 22-24 March 2024