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Vontas JG, Small GJ, Hemingway J

High uric acid promotes dysfunction in pancreatic cells by blocking IRS2/AKT signalling

Vitamin C also enhances the activity of a large family of iron (Fe 2+ ) and -ketoglutarate-dependent dioxygenases (-KGDDs), which include epigenetic regulators of DNA methylation known to play important roles in the maintenance of genomic stability