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60 PachettiM.MariniB.BenedettiF.GiudiciF.MauroE.StoriciP.et al (2020)

Interestingly, when SIRT5 deletion is restricted to the heart, survival rates remain unaffected compared to controls, despite marked accumulation of succinylated mitochondrial proteins, indicating that SIRT5s cardioprotective effects may be systemic or developmental [118]