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Nature medicine 2016;22, 7883, doi: Schoenwaelder, S

Stimulated by gentamicin and other poisons, TLR4 on KCs surface is activated, and TNF-, IL-6 and other pro-inflammatory factors are secreted through MyD88-dependent pathway (Yang et al., 2022

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It is used clinically and in research for tissue repair, with studies covering tendon and ligament injury, muscle strain, gut lining damage (including ulcers and inflammatory bowel conditions), and post-surgical recovery