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They can be managed at home with the following interventions: Over-the-counter oral antihistamines like Claritin or Zyrtec Topical hydrocortisone cream to reduce swelling Cold compresses to ease itching Calamine lotion to soothe skin Oatmeal baths to reduce inflammation However, you should consult a doctor right away if you experience: Hives that cover large portions of the body Rapid swelling of the face, lips, or around the eyes Wheezing, chest tightness, trouble breathing, or swallowing Dizziness, fainting, or heart palpitations Severe itching that oral antihistamines dont relieve These can be signs of a serious allergic reaction that requires immediate treatment with an epinephrine autoinjector (EpiPen) and emergency medical care

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Ablation of astrocytes, or inhibition of astrocyte specific homoeostatic molecules in experimental animals trigger behavioural abnormalities that resemble neuropsychiatric symptomatology in humans

Adagrasib (Ada) + cetuximab (Cetux) for KRASG12C-mutated metastatic colorectal cancer (mCRC): Longer follow-up analysis from KRYSTAL-1