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What medications should not be taken with B12

Isatuximab interacts with a discontinuous epitope partially overlapping the catalytic site, whereas Daratumumab binds to two continuous amino acid sequences situated outside the enzymatic active site of CD38 ( i.e

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A further small study done recently on 10 paediatric patients similarly found that intranasal OH-Cbl normalised serum B12 levels in deficient patients ( Subcutaneous B12 Subcutaneous B12 is occasionally used, especially in patients with inborn errors of cobalamin metabolism, who need high pharmacological doses of B12 to maintain their B12-dependent metabolic pathways and related biochemistry within normal range

This is a later sign, appearing when B12 deficiency has persisted for a long time