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The formation of GSH conjugates to phenyl arsine oxide (another arsenic-based drug) results in the inhibition of GSTP1 action [134], highlighting another example of cellular signaling by GSH S-conjugates

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These findings suggest that research into the therapeutic modulation of FOXO4 activity, such as through the use of the synthetic peptide FOXO4-DRI, could provide insight into the heart's natural protective mechanisms and degenerative changes associated with aging

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