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The details of the interactions between gH/gL and cell surface receptors, and the molecular mechanisms by which it activates gB, are poorly understood

Homocysteine is a thiol-containing amino acid, which suffers two major metabolic fates: remethylation catalyzed by methionine synthase (MS), methylenetetrahydrofolate reductase (MTHFR) or betaine-homocysteine methyltransferases (BHMT) and transsulfuration catalyzed by cystathionine -synthase (CBS) leading to cystathionine [3] (Figure 1)

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Possible rare reactions: Mild irritation Sensitivity in compromised skin Patch testing is always recommended