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Back pain is one of the most common health conditions in the United States, and it is one of the more expensive to treat

The emergence of the exposome concept has transformed our understanding of how environmental factorsincluding health-promoting exposures such as plant-derived compoundsinteract with the human genome to influence health trajectories across the lifespan

The mechanism: hypothalamic GHSR-1a activation triggers CRH release pituitary corticotroph activation ACTH adrenal cortisol production

Trimethylamine N-oxide in atherogenesis: impairing endothelial self-repair capacity and enhancing monocyte adhesion

Thomas et al., 2009