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2.7.1 Basic science research The three specific sensor proteins of ER stress are activating transcription factor 6 (ATF6), inositol requiring enzyme 1 (IRE1), and eukaryotic pancreatic ER kinase (PKR)like ER kinase (PERK): each one activates subsets of effector genes comprising ATF4, caspase-12, CHOP, bcl, and NF-B

Historically, collagenase as a TOPICAL is a cream that can be applied to severe burns or skin ulcers to help remove dead skin tissue

Several factors support the theoretical viability of oral BPC-157, though human outcomes remain unproven: Gastric Stability: BPC-157 was originally studied for gastric protection in animal models, meaning the compound was administered directly into the stomach in research settings

Aguila MC, Marubayashi U, McCann SM

Neil S., Huh J., Baronas V., Li X., McFarland H.F., Cherukuri M., Mitchell J.B., Quandt J.A