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Reality : Loses significant potency within hours to days

This leads to destabilisation of ionic gradients and subsequent water influx and membrane rupture (Ding et al

Avoid the use of Lamictal in patients who have cardiac conduction disorders (i.e., second- or third-degree heart block), ventricular arrhythmias, or cardiac disease or abnormality (i.e., myocardial ischemia, heart failure, structural heart disease, Brugada syndrome, or other sodium channelopathies)

The committees recommendations are non-binding, but they often shape what the FDA later allows compounding pharmacies to prepare for patients

Early identification of these risk factors is essential for implementing targeted prevention strategies and designing personalized rehabilitation programs [22,32]