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Such physiological clearance mediated by the hair-like cilia on the surface of epithelial cells with their fluctuating movement is responsible for the clearing of nasally administered drugs from the nose with a half-life of 21 min (Ozsoy et al., 2009)

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(ii) As a delayed regimen, the therapy (BPC 157 or saline (5 mL/kg)) was given as an intragastric administration at 4.30 h of ligation time for assessment at 5 h of ligation time, or BPC 157 as an oral administration, given continuously in drinking water from 5 h of ligation time until the sacrifice at 24 h of ligation time (0.16 g/mL/rat, 0.16 ng/mL/rat) while controls received drinking water only (12 mL/day/rat)