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In fact, it is often called the master antioxidant or the mother of all antioxidants

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J.YangW.DongL.BradleyH.et al (2008)

Notably, the enzymatic activity of GPX4 is strictly dependent on its active-site selenocysteine residue (168), implying that dietary selenium intake directly regulates GPX4 protein expression and functional activity, thereby determining cellular susceptibility to ferroptosis