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Another possible mechanism by which CS alters AHR could be due to an impact on airway smooth muscle (ASM), either the increased ability to contract [76] or the remodelling changes reported such as increased ASM thickness via antigen induced increase in proliferation/migration associated with the AHR phenotype [77]

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William McKinley, the twenty-fifth president, who was assassinated in 1901, neither smoked in public nor permitted himself to be photographed with a cigar, but in private he was nearly obsessive about having his smoke Three-hundred-pound William Howard Taft entered his presidency, the twenty-seventh man to hold the position, as a cigar smoker, but he quit while in office

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