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Furthermore, with respect to the healthy control group of mice, all benzo[a]pyrene LCA-induced mouse groups treated with laser, high-frequency ultrasound, or combination of laser and high-frequency ultrasound solely exhibited a significant reduction in levels as well as Catalase, SOD, TAC, GR, GPx and GST activities

The level of PCs was significantly higher in Rib (+ 49%) and Rib + NAC (+ 28%) than in BSA (Fig

The genes are found in the hla-d region in humans and include h-2m, i-a, and i-e loci in mice

Larsson, A., Wilhelmsson, U., Pekna, M

Altogether, these pathways form a tightly integrated network, where oxidative stress, inflammatory signaling, and apoptosis reinforce one another, while regulatory pathways such as Nrf2/HO-1, SIRT1, and -Klotho are suppressed, shifting the cellular balance toward damage and follicular loss