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Discussion In the present study, we demonstrated that permanent IGF-1 attenuated oxidative SIPS of hepatocytes via inhibiting the interaction between nuclear p53 with progerin (Fig

The current finding is in harmony with prior studies where RVX possessed an anti-oxidant effect in cisplatin-induced testicular damage 35 , renal injury induced by sunitinib 52 , and sunitinibinduced cardiotoxicity 53 .Oxidative stress results from the imbalance between the formation of ROS and anti-oxidants

It is still unclear whether changes in microbiota directly cause changes in bile acids, whether bile acids have an effect on the microbiota, or whether both are outcomes of LT therapy

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