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Cells were pelleted at 5200 g for 10 min at 4 C

Thrombocytopenia A decrease in the number of platelets in the blood

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[18] characterized microbial HAases (mHyals) as Mn 2 /Ni 2 -sensitive enzymes with optimal activity at 3745 C and pH 5.57.0 [54], mHyals serve as virulence factors that mediate bacterial invasion, tissue penetration, and dissemination [55, 56]