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Rapamycin relieves the cataract caused by ablation of Gja8b through stimulating autophagy in zebrafish

YangYChenLZhangNZhaoYCheHWangYet al

Zhang Y, Li M, Han X

This ROS-independent lethality is attributed to mismetallation, wherein copper displaces essential metal cofactors such as Fe 2+ and Zn 2+ in metalloproteins, resulting in functional inactivation (Zuily et al., 2022)