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These data suggest that glutathione depletion, rather than increased ROS generation, has a stronger effect on promoting methylglyoxal sensitivity

Methylmalonic Acid (MMA) Test: Doesnt check B12 directly, but if MMA is high, it usually means your body isnt absorbing/using B12 properly, even if your B12 levels look normal

doi: 10.1158/2159-8290.CD-21-0030 12 de GrootSLugtenbergRTCohenDWeltersMJPEhsanIVreeswijkMPGet al

found that AS-IV improved hyperglycemia, insulin resistance, and glucose tolerance in diet-induced and genetically obese mice by elevating circulating levels of adiponectin (Xu et al., 2009)