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Considering the important role of the above aspects in PNI, it is feasible to explore the mechanism of PNI by studying the interaction between cancer cells and nerves, the expression of neurotrophic factors, and the invasion and migration ability of cancer cells in the process of PNI

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the behavioral testing protocol has been described previously in detail (Wright et al., 1999)

One side shows normal reeding, the other looks smooth and slightly beveled