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Injections are done every 1 cm and with each injection about 0.1 to 0.2 mL of the steroid is administered

However, challenges such as the long-term survival and integration of transplanted cells within the hostile ALS microenvironment remain significant hurdles in preclinical models (60, 61)

In addition, SlBEL11 gene silencing resulted in changes in the expression of core enzyme genes in the carotenoid metabolic pathway, including PSY1 , P SY2 , PDS , ZDS , LCY-b1/b2 , CYC-b , and LCY-e