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Statins are potent inhibitors of HMGCR, which plays a crucial role in controlling cholesterol biosynthesis through the mevalonate pathway (MVA) (Yu et al., 2017)

One study specifically identified the infection as a risk factor of cardiovascular disease development in elderly G6PD-deficient patients [51]

Accurate differentiation between NAFLD subtypesincluding NAFL, NASH, and fibrosiscontinues to rely heavily on histopathological analysis, constraining epidemiological stratification and longitudinal assessments [103, 104]

In CNS-relevant models, melanocortin receptor activation is used to probe appetite suppression and neuroendocrine arousal circuitry, including receptor desensitization dynamics in time-course assays