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2020 Jan Anna N Ligezka, A Irem Sonmez, Martha P Corral-Frias, Raphael Golebiowski, Brian Lynch, Paul E Croarkin, Magdalena Romanowicz

These decrease over time for most researchers

These healthspan improvement findings have profound implications for longevity research, development of geroprotective therapies, and understanding how senescent cell accumulation contributes to the functional decline characteristic of biological aging

MOTS-C supports muscle protein synthesis and metabolic health, helping maintain lean muscle mass during aging and supporting healthy body composition and physical function

3C, D and Supplementary Fig