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Patients have reported aesthetic benefits, such as: Improved skin texture Enhanced skin tone Increased firmness Better elasticity Reduction in the appearance of fine lines Improvements in skin quality are typically reported within four to eight weeks

Lupus nephritis (LN)the most severe SLE manifestationaffects most patients within 5 years of diagnosis, with ~10% progressing to end-stage kidney disease (ESKD) (212)

Data are shown as mean values SEM of four independent experiments

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