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96 A trial in which 115 participants received 600 mg fenugreek extract or placebo daily for 12 weeks found fenugreek reduced hot flashes, night sweats, and psychosocial, physical, and sexual symptoms as well as overall menopausal symptom scores, without affecting E2 levels

Reid, A

It acts as a potent - and -opioid receptor agonist, with an EC50 of nearly 15 nM for both receptor types [156], providing effective pain modulation with reduced risk of side effects associated with classic opioids [157,158,159]

It is also found in foods such as meats, fish, nuts, beans, spinach and eggs

In biochemical and cellular research models, BPC-157 has been reported to interact with multiple signalling pathways, including nitric oxideassociated mechanisms, growth factor-related signalling, and cytoskeletal regulatory processes