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Mitochondrial transplantation exhibits neuroprotective effects and improves behavioral deficits in an animal model of Parkinsons disease

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Liesz et al [57] found that T reg cells antagonize enhanced TNF- and IFN- production, which induce delayed inflammatory brain damage, and that T reg cell-derived secretion of IL-10 is the key mediator of the cerebroprotective effect via suppression of proinflammatory cytokine production