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At high concentrations, direct parasympathetic cardiac inhibition overrides the baroreceptor-mediated reflex response, resulting in bradycardia with prolonged RR intervals on ECG

Statins act as competitive inhibitors of HMG-CoA reductase, the enzyme that limits the rate of cholesterol production in hepatocytes, thereby decreasing cholesterol synthesis

Schott, B., Zhu, A., Szirth, B

Hepatitis c virus contributes to hepatocarcinogenesis by modulating metabolic and intracellular signaling pathways