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Rodent studies Thirteen preclinical studies investigated the effect of polyphenol supplementation on the later-life consequences of ES

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doi: 10.2147/DDDT.S521265 54 FrkW.DbekB.Balcerczyk-LisM.MotorJ.RadziochE.MynarskaE.et al

In addition, the classical ferroptosis inducer erastin was also reported to damage cardiomyocytes by initiating ferroptosis, while ENPP2, a lipid kinase generating the lipid mediator lysophosphatidic acid, could protect cardiomyocytes from the erastin-induced ferroptosis by decreasing ROS generation [107]