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During niacin treatment, fasting glucose, insulin and HOMA1-IR (insulin resistance score based on blood glucose and insulin) increased in some individuals up to 1.9-fold after niacin dose of 500 mg, suggesting increased insulin resistance (Fig

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This indicates that most microorganisms of the gut microbiota may degrade and metabolize mucin glycans

Selepe MA, Kunyane P, Seboletswe P, Nair S, Cele N, Engelbrecht M, Joubert DF, Vandevoorde C, Singh P, Sonopo MS (2022) Synthesis and evaluation of benzoylbenzofurans and isoflavone derivatives as sirtuin 1 inhibitors with antiproliferative effects on cancer cells