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10.1113/EP091707 161 KovacevicA.MavrosY.HeiszJ

Lung tissue and sample preparation In each group, the left lungs of 6 mice were infused with 0.5 ml PBS three times for the harvest of bronchoalveolar lavage (BAL) fluid, while the left lung tissues of the other 6 mice were inflated with 10% neutral formaldehyde at positive pressure (25 cm H 2 O) (Glynos et al., 2018

Unlike other organelles such as mitochondria, where an abundance of reduced glutathione (GSH) preserves a reductive environment, the ER requires an oxidizing milieu to facilitate the formation of disulfide bonds critical for protein structural integrity

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Rho - yeast, which have only partial fragments of mtDNA and co-incident defects in oxidative phosphorylation (oxphos)