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Additionally, ATF6 forms a heterodimer with IRE1-XBP1 pathway to activate the genes involved in ERAD [126]

Nakai Y, Inoue K, Abe N, Hatakeyama M, Ohta KY, Otagiri M, et al

This regulation is facilitated by the action of hormones (glucagon and insulin), central and peripheral nervous system, as well as metabolic requirements of the body [37]