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In some specific research protocols, alternatives are used: Sterile water for injection (WFI) , when the entire contents of the vial are used at once and a preservative is not needed Physiological saline (0.9% NaCl) , in some applications requiring an isotonic environment Acidic solvents (e.g

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Results showed that JETALS met its main goal, with methylcobalamin-treated patients showing significantly less decline in their ALSFRS-R scores than those given a placebo (2.66 vs