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Additional mouse studies have shown that Indian hedgehog ( Ihh ), TSC1 , and Wnt/cat are required for AF formation (Maeda et al., 2007

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10.1016/j.mito.2010.05.014 Mitochondrion 507 WuZ.HuangX.FengY.HandschinC.FengY.GullicksenP

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As expected, statin-treated males and females both experienced reduced levels of hepatic cholesterol species (females had reduced free cholesterol, and males reduced cholesterol esters), and both showed trends to very modest reductions in mevalonate pathway intermediates (females reduced geranylgeranyl pyrophosphate, and males trended to reduced CoQ 10 and farnesyl pyrophosphate) (Suppl

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