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In addition, PAC has the capacity to reduce fever and pain as well as NSAIDs ( The routinary use of PAC in at risk categories, along with their intrinsically frail conditions, may have further worsen the scarcity of GSH, especially in western countries where PAC consumption is particularly high

Modern pharmacological studies have reported that tetramethylpyrazine (TMP), an active metabolite in Ligusticum chuanxiong , possesses various physiological functions, including antioxidant capabilities, anti-inflammatory actions, anti-apoptotic characteristics, the ability to regulate autophagy, vasodilatory functions, modulation of angiogenesis, inhibition of mitochondrial damage, safeguarding of endothelial cells, and mitigation of vascular smooth muscle cell proliferation and migration, and also offers neuroprotective benefits ( in vivo experiments using a mouse model of focal ischemic stroke (IS), TMP upregulates the expression of monocyte chemoattractant protein-induced protein one to inhibit neuroinflammatory responses, while protecting the integrity of the BBB ( Ligusticum chuanxiong

However, suitability varies depending on individual health status

doi: 10.1590/0001-3765201920190434

BAC water's benzyl alcohol prevents contamination