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10.1111/j.0954-6820.1986.tb02790.x 37 BernsteinA.OdzeM.CrewsA.Jr.SimonF

A total of 1015% of ALS can be attributed to a single gene mutation, known as genetic or familial ALS, while the remainder of cases are termed nongenetic or sporadic although heritability has been measured in up to 37% in this population

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In breast cancer cells, loss of the tumor suppressor gene PTEN is frequently observed

10.1016/j.cell.2018.09.021 [DOI] [PMC free article] [PubMed] [Google Scholar] Reddien P