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Polyunsaturated fatty acids (PUFAs) have been shown to reduce hepatic triglyceride accumulation, while diets high in the n-6/n-3 PUFA ratio and low in total PUFA content are linked to the development of fatty liver and other chronic metabolic disorders [75, 76]

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Autophagy plays a crucial role in progesterone-mediated reproductive function, as demonstrated by experimental research that shows deletion of autophagy-related proteins, such as FIP200, reduces progesterone responsiveness and causes pathological inflammation [179]

To view a copy of this license, visit About this article Cite this article Bidabadi, S.S., VanderWeide, J