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[PubMed] [Google Scholar][143] Parodi MB, Saviano S, Ravalico G

Additionally, as AMPK is an endogenous energy sensor that regulates lipid and carbohydrate metabolism, Folate mediates AMPK activation by promoting AMP elevation and activation of its upstream kinase liver kinase B1 (LKB1), Folate supplementation restores AMPK phosphorylation activation and reduces blood glucose and liver cholesterol levels