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The biology is doing what the theory predicts

This article outlines an approach to interpreting and working up a high serum B12 in adults by separating four possibilities: intake-related elevation, disease-associated hypercobalaminemia (an elevated blood B12 associated with an underlying condition), analytical interference, and functional deficiency

During the last two decades, new technologies for generating mouse/human chimeric monoclonal antibodies and humanized monoclonal antibodies have resulted in more successful clinical antibody applications

doi: 10.3389/fendo.2025.1520835, 148

While sun exposure can worsen melasma, the root trigger is hormonal fluctuation