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Despite the availability of anti-seizure medications, approximately 30% of patients remain drug-resistant, emphasizing the pressing need for alternative therapeutic strategies

Functionally, no-DAC CJC-1295 acts like a somewhat longer-lasting GHRH signal: it binds the pituitary GHRH receptor, a G-protein-coupled receptor that raises intracellular cyclic AMP in somatotroph cells, and pushes those cells to synthesize and release GH but only for a window measured in minutes to a couple of hours, not days

236 Moreover, the mucosal regulator carbocisteine has a similar effect

Am J Ophthalmol 2009