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Furthermore, existing studies have not adequately distinguished the relative contributions of transcriptional upregulation of GPX4 versus increased protein stability to the outcomes, leaving some mechanistic explanations still at the inferential level

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A titrated dose of 150 g/day is generally recommended [34, 50, 51]

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The similarity included a hydrophobic domain (amino acids 1228) similar in location to the transmembrane domain of GGT, indicating that GGT-rel is also a type II membrane protein with the active site on the cell surface