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Patients should be educated about the importance of preventing freezing and should take precautions when transporting the medication, particularly during cold weather

Genetically, they are characterized by balanced chromosomal translocations in which a member of the FET gene family is fused with an ETS transcription factor, with the most common fusion being EWSR1FLI1 (85% of cases)

In the colon, xylitol is fermented by gut microbiota and studies with human faecal cultures suggest xylitol might act as a prebiotic, increasing the formation of short-chain fatty acids such as butyrate

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