glutathione reductase formula Schematic representation of the role of the enzyme File:Reductive half-reaction of glutathione reductase.png

Targeting NLRP3 (nucleotide-binding domain, Leucine-rich-containing family, Pyrin domain-Containing-3) Inflammasome in cardiovascular disorders

Cells were washed once with PBS and collected after adding iron analysis solution

Such an integrated strategy holds promise for elevating the effectiveness of epigenetic therapies in AML

Ye et al., 2002)

Importantly, these findings were later corroborated by in vivo studies where both acute (single high-dose striatal injection) and sub-chronic (21 days of 30 mg/kg intranasal Mn) exposure reduced GLAST/GLT-1 expression and were associated with motor deficits, at doses approximating human Mn exposure (Johnson et al., 2018