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Folates are essential for DNA synthesis and cell division, meaning they support the growth of healthy cells but may also accelerate the growth of existing pre-cancerous or cancerous cells

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J Clin Diagn Res 8(12):CD01CD02 Rossi E, Taketani S, Garcia-Webb P (1993) Lead and the terminal mitochondrial enzymes of haem biosynthesis

The dopamine downregulation or disabled response of receptors is what is likely behind the prevalence of addiction developing with continued use or abuse of stimulant-based medications