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This resistance is mediated by different causes and mechanisms, (that are resumed in Table 1 and excellently summarized in different review articles [78].One of the most obvious and intriguing mechanisms of resistance involves alteration in CD38 expression, a crucial factor in both primary and acquired resistance to anti-CD38 therapies

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Metabolic syndrome For many decades, the concept of clustering metabolic disorder and CVD risk factors has been widely discussed

The Great Cavern: The Great Cave is a natural formation that was used by the Incas for ceremonial purposes

We're all different and our pain thresholds are also different