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670,671 In a TBI mouse model, DFO has been shown to mitigate acute brain edema and long-term neurotoxicity induced by iron deposition, improve grip strength and prognosis in mice

It functions as an electron carrier in cellular respiration and as a substrate for sirtuins (longevity proteins) and PARP enzymes (DNA repair proteins)

Suppression of the ELO-2 FA elongation activity results in alterations of the fatty acid composition and multiple physiological defects, including abnormal ultradian rhythms, in Caenorhabditis elegans

Current Neuropharmacology .

However, oral supplements are usually preferable as they dont require any complicated dietary changes